21C MUSEUM HOTEL LOUISVILLE, Louisville – Your ideal downtown stay

21C Museum Hotel Louisville - Boutique hotel with contemporary art exhibits near Muhammad Ali Center

Located in downtown Louisville, this hotel combines a contemporary art museum with a 91-room boutique hotel. Guests have access to over 9,000 square feet of exhibition space featuring curated global artworks. The property is within a half mile of the Kentucky Museum of Art & Craft, Frazier International History Museum, and Muhammad Ali Center. Dining options include Proof on Main, serving southern and Appalachian-inspired cuisine with a bourbon bar. The free electric ZeroBus stops two roads away, providing access to downtown attractions like Whiskey Row and Slugger Field. The hotel offers a 24-hour fitness center, sauna, steam room, and pet-friendly rooms.

Additional perks of the hotel

Free access to rotating contemporary art exhibitions

Onsite Reflexology treatments focusing on reflex points in feet, hands, and ears

Event spaces for 10-60 guests with tailored catering by Proof on Main

River City Tintype offers historic photography experiences

Eco-conscious meeting planning available

Private bourbon barrel program at Proof on Main lounge

Rooms & Suites

Guest rooms feature original artwork and premium Bryte Restorative Sleep Beds with adjustable temperature and firmness. The Atrium Suite includes a king bed, living/dining area, tub, and walk-in shower. Corner Suites offer four windows with views of 7th Street, Main Street, and the Ohio River. The Asleep in the Cyclone suite is an artist-designed installation with a king platform bed, record player, and curated components. All accommodations include 50-55" HDTVs, Lavazza coffee, and Malin+Goetz bath amenities.

Other conveniences

Ironing facilities and trouser press in rooms

Mini-bar and tea/coffee maker

Soundproofed rooms with carpeted floors

Private bathrooms with free toiletries and bathrobes

Some rooms feature city views

Laundry service available